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Tuberous sclerosis complex tumor suppressors : ウィキペディア英語版 | Tuberous sclerosis complex tumor suppressors
Tuberous sclerosis complex (TSC) tumor suppressors form the TSC1-TSC2 molecular complex. Under poor growth conditions the TSC1-TSC2 complex limits cell growth. A key promoter of cell growth, mTORC1, is inhibited by the tuberous sclerosis complex.〔 Insulin activates mTORC1 and causes dissociation of TSC from the surface of lysosomes. Resistance to ischemia-reperfusion injury by protein restriction is mediated by activation of the tuberous sclerosis complex. ==References==
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Tuberous sclerosis complex tumor suppressors」の詳細全文を読む
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